Summary: A functional electron transport chain (ETC) is crucial for supporting bioenergetics and biosynthesis.Accordingly, ETC inhibition decreases proliferation in cancer cells but does not seem to impair stem cell proliferation.However, it remains unclear how stem cells metabolically adapt.In this study, we show that pharmacological inhibition bu
Background Subclassification of ovarian carcinomas can be used to guide treatment and determine prognosis.Germline and somatic mutations, loss of heterozygosity (LOH), and epigenetic events such as promoter hypermethylation can lead to decreased expression of BRCA1/2 in ovarian cancers.The mechanism of BRCA1/2 loss is a potential method of subclass
Most cells exchange ions and small metabolites via gap junction channels.These channels are getpureroutine.com made of two hemichannels (connexons), each formed by the radial arrangement of six connexin (Cx) proteins.Connexins span the bilayer four times (M1-M4) and have both amino- and carboxy-termini (NT, CT) at the cytoplasmic side of the membra
Ultraviolet (UV)-induced degradation is one of the major problems in the field of perovskite solar cells (PSCs).Therefore, exploring materials and techniques to prevent UV light from penetrating into the device is urgently necessary.Here, we developed a special transparent fluorinated polyimide (FPI) resin, which can be directly iphone 13 atlanta s